using the registry

## 1. Accessing the System

### Initial Setup

1. Contact your institutional registry administrator to request access

2. Complete required training modules

3. Sign confidentiality agreements and data handling protocols

4. Receive your unique user credentials

5. Download and install the security certificate for your browser

### Logging In

1. Access the secure portal at your institution's designated URL

2. Enter your username and password

3. Complete two-factor authentication using your registered device

4. Select your role-specific workspace

## 2. Patient Registration

### New Patient Entry

1. Click "New Patient Registration" in the main dashboard

2. Enter the unique patient identifier using your institution's coding system

3. Complete mandatory fields:

   - Demographic information (using standardized formats)

   - Primary diagnosis

   - Cell therapy protocol identifier

   - Treatment center information

   - Informed consent documentation

4. Upload required documentation in specified formats

5. Submit for validation

### Updating Patient Records

1. Search for existing patient using the secure search function

2. Select "Update Record"

3. Choose the appropriate section for modification

4. Document reason for update

5. Save changes with digital signature

## 3. Data Entry Guidelines

### Treatment Data

1. Record all cell therapy procedures using standardized terminology

2. Document collection dates and times

3. Enter processing facility information

4. Record product characteristics

5. Document administration details

6. Note any immediate adverse events

### Follow-up Data

1. Schedule follow-up visits in the system

2. Record outcomes using standardized assessment tools

3. Document adverse events using common terminology criteria

4. Upload relevant laboratory results

5. Update quality of life measures

## 4. Data Quality Management

### Quality Checks

1. Review automated data validation alerts

2. Address any flagged inconsistencies

3. Complete missing mandatory fields

4. Verify uploaded document quality

5. Confirm coding accuracy

### Error Correction

1. Flag erroneous entries using the "Report Error" function

2. Document reason for correction

3. Submit correction request

4. Track correction status

5. Verify implemented changes

## 5. Reporting Functions

### Standard Reports

1. Access the reporting module

2. Select report template

3. Define parameters (date range, patient cohort, etc.)

4. Generate report

5. Export in approved format

### Custom Queries

1. Use the query builder interface

2. Select relevant data fields

3. Define inclusion/exclusion criteria

4. Apply necessary filters

5. Save query for future use

## 6. Safety and Security Practices

### Data Protection

1. Never share login credentials

2. Log out after each session

3. Use secure networks only

4. Report suspicious activities

5. Maintain workstation security

### Privacy Requirements

1. Verify patient consent status before accessing records

2. Document purpose for each data access

3. Use de-identified data for reports

4. Follow minimum necessary principle

5. Report privacy breaches immediately

## 7. Support and Resources

### Technical Support

1. Contact local registry support for immediate assistance

2. Submit help desk tickets for non-urgent issues

3. Access online troubleshooting guides

4. Document technical issues encountered

5. Participate in user feedback sessions

### Training Resources

1. Access online training modules

2. Review updated standard operating procedures

3. Participate in scheduled refresher training

4. Download user guides and quick reference materials

5. Join user community forums

## 8. Special Considerations

### International Data Entry

1. Use standardized international date formats

2. Follow language protocols for free text fields

3. Apply appropriate unit conversions

4. Note time zones for time-sensitive data

5. Follow country-specific privacy requirements

### Research Protocols

1. Link registry entries to approved research protocols

2. Follow protocol-specific data collection requirements

3. Document protocol deviations

4. Maintain research cohort identifiers

5. Apply protocol-specific quality measures